Our ability to measure the RNA landscape in health and disease is improving rapidly, powered by long-read, single cell and spatial transcriptomics. Realising these advances requires new computational methods for discovery and interpretation, since the transcripts that matter most in cancer are often the ones absent from reference catalogues. This talk focuses on the altered transcripts that drive cancer: the novel splice variants, gene fusions, and structural rearrangements hidden within tumour transcriptomes and the methods my lab has built to find them.

About the speaker: Dr. Nadia Davidson is a Laboratory Head and NHMRC Emerging Leader Fellow at the Walter and Eliza Hall Institute. She completed a PhD in Particle Physics at the University of Melbourne (2011) before retraining in bioinformatics under Prof. Alicia Oshlack, at the Murdoch Children’s Research Institute (2011–2019) and the Peter MacCallum Cancer Centre (2019–2021). The Davidson Laboratory, established in 2022, develops methods for transcriptome sequencing analysis, focused on novel transcript discovery, and collaborates on projects using short-, long-, bulk- and single-cell sequencing to uncover new insights in cancer.

Join us: ACMD Auditorium

Level 1, 27 Victoria Parade, Fitzroy

(enter via Nicholson Street)

13 October, 12:00pm – 1:00pm